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| Desriac, Florie; El Harras, Abderrafek; Simon, Matthieu; Bondon, Arnaud; Brillet, Benjamin; Le Chevalier, Patrick; Pugnière, Martine; Got, Patrice; Destoumieux-garzón, Delphine; Fleury, Yannick. |
| Discovery after discovery, host-associated microbiota reveal a growing list of positive effects on host homeostasis by contributing to host nutrition, improving hosts’ immune systems and protecting hosts against pathogens. In that context, a collection of oyster associated bacteria producing antibacterial compounds have been established to evaluate their role in non-host-derived immunity. Here, we described alterins; potent anti-Gram negative compounds produced by Pseudoalteromonas hCg-6 and hCg-42 isolated from different healthy oyster hemolymph. The strains hCg-6 and hCg-42 produce a set of at least seven antibacterial compounds, ranging from 926 to 982 Da structurally characterized as cyclolipopeptides (CLPs). Alterins share the same cationic... |
| Tipo: Text |
Palavras-chave: Pseudoalteromonas; Cyclolipopeptides; Alterin; Antibiotic. |
| Ano: 2020 |
URL: https://archimer.ifremer.fr/doc/00663/77511/79275.pdf |
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| Mosbah, Amor; Delavenne, Emilie; Souissi, Yasmine; Mahjoubi, Mouna; Jehan, Philippe; Le Yondre, Nicolas; Cherif, Ameur; Bondon, Arnaud; Mounier, Jerome; Baudy-floc'H, Michele; Le Blay, Gwenaelle. |
| Lactobacillus harbinensis K.V9.3.1Np was described as endowed with high antifungal activity. Most of the studies associated this activity to the produced organic acids, i.e., lactic acid, acetic acid, and hexanoic acid. The aim of this study was to purify and identify, other not yet described, antifungal molecules produced by L. harbinensis K.V9.3.1 Np when used in yogurt fermentation. Active compounds were extracted through several extraction processes using organic solvents and protein precipitation. The fractions of interest were purified using flash chromatography and preparative HPLC for specific characterization. The bioactive compounds identification was performed using Nuclear Magnetic Resonance and Mass Spectrometry. Activity tests against... |
| Tipo: Text |
Palavras-chave: Spermine; Polylactates; Lactobacillus; Extraction; Purification; Ms; Nmr. |
| Ano: 2018 |
URL: https://archimer.ifremer.fr/doc/00616/72773/72221.pdf |
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